Main Article Content

Abstract

Diabetes mellitus is a chronic condition that disturbs the body's blood sugar
regulation. This disorder is characterized by a decrease in the ability of body
cells to intake glucose into cells. Due to the failure of cells in glucose intake,
glucose buildup occurs in the extracellular, namely in the plasma. These
medicinal plants contain quite varied secondary metabolites, where these
plants are rich in flavonoids, alkaloids, terpenes and glycosides. The content
of these secondary metabolite compounds is believed to be rich in antioxidant
effects so that it has the effect of being able to suppress various oxidative
stress conditions that cause damage to various organs due to blood sugar
dysregulation. The effect of Tinospora crispa, Andrographis paniculata,
Cinamomum burmanii, Syzygium polyanthum and Momordica charantia
extracts on blood sugar levels and GLUT4 protein expression in muscle tissue
shows the potential of the test extract's ability to improve blood glucose intake
to cells so as to maintain blood sugar regulation.

Keywords

Tinospora crispa Andrographis paniculata, Cinamomum burmanii Syzygium polyanthum Momordica charantia Diabetes Mellitus Muscle Rats

Article Details

How to Cite
Hidayat, R., & Patricia Wulandari. (2021). Potential Combination of Tinospora crispa, Andrographis paniculata, Cinamomum burmanii, Syzygium polyanthum and Momordica charantia Extracts Against Intake of Glucose in Muscle Rats-Induced Diabetes Mellitus. Eureka Herba Indonesia, 2(1), 68-72. https://doi.org/10.37275/ehi.v2i1.14